Some of the previously isolated constituents in vernonia amygdalina del. Vernonia amygdalina has also been fed to broilers, where it was able to replace 300 g kg1 of maizebased diet without affecting feed intake, body weight gain and feed efficiency teguia et al. Phytochemical and pharmacological prope of vernonia. Vernonia amygdalina va is a woody shrub reported to have not only diverse therapeutic effects but also anticancer properties. Native to nigeria west africa and widely grown in africa, va is also found in asia, and is especially common in singapore and malaysia. Vernonia amygdalina del asteraceae is a small shrub with dark green leaves and rough barks growing predominantly in tropical africa but has been domesticated in many parts of west africa igile et al. Vernonia amygdalina va has many usages in tropical africa, either for food or medicinal purposes. Vernonia amygdalina is a widely grown shrub plant in africa consumed as vegetable and has high medicinal value. Vernonia amygdalina has been a known food and medicinal plants used in asia and. These chemical elements contained in the aqueous extract of vernonia amygdalina allow it to have a very powerful phytotherapeutic potential adebayo and al.
The aim of this research study was to determine the chemical composition and invitro anthelmintic activity of vernonia amygdalina extract. The anticancer activities of vernonia amygdalina extract. The resulting powdered extract was used in running a phytochemical test. Phytochemical screening of vernonia amygdalina leaves grown with and without the addition of plant protection products is carried out and presented intable 2. Isolation, structural elucidation, and bioactivity studies. Essential oil composition, nutrient and antinutrient analysis of vernonia mespilifolia less research journal of botany 2017, 12 2, 3845.
Accepted 22 january, 20 this research was carried out on the aqueous extracts of bitter leaf vernonia amygdalina to evaluate. However, current research about the mechanisms of the anticancer potential of va. Nutritional, therapeutic and toxicological risk assessment. Chemical constituents and nutrient composition of carica. It is a perennial plant with height between 1 m and 6 m nwosu et al. Nutritional, therapeutic and toxicological risk assessment of. Journal of complementary and alternative medical research, issn. Prospective bioactive compounds from vernonia amygdalina. Toward the chemical ecology of medicinal plant use in. Isolated from the plant were four known sesquiterpene lactones, seven new steroid glucosides, and two aglycones of the glucosides. The young leaves are used as an antihelmintic, antimalarial, laxativepurgative, enema, worm expeller and fertility inducer in subfertile women. Vernonia amygdalina phytochemicals and medicinal plants.
The leaves exhibit a characteristic odor and bitter taste, explaining its common english. Isolation, structural elucidation, and bioactivity studies of. Pdf on jan 10, 2017, okpe oche and others published chemical constituents and nutrient composition of carica papaya and vernonia amygdalina leaf extracts find, read and cite all the research. Evaluation of antioxidant and cytotoxic properties of vernonia. Antioxidant properties, bioactive compounds, chemical composition, health benefits, vernoniaamygdalina. Experimental details materials preparation mild steel of composition wt% mn 0. Comparative study of condiment vegetable basil leaf. Effect of different processing methods on nutritional. Vernonia amygdalina is a valuable medicinal plant that is widespread in west africa, it is known as bitter leaf due to its characteristic bitter taste and flavour, and canbe used as an active anticancer, antibacterial, antimalarial and antiparastic agent. Chemical composition of vernonia amygdalina collected form different reference. Material and methods a healthy and improved authenticated breed of vernonia amygdalina used for this study was obtained from vegetable garden located near erelu dam of oyo town and authenticated. Breast cancer is currently the leading cause of cancerrelated deaths among women globally. Phytochemical constituents and ethnobotany of the leaf. Comparative chemical analyses of vernonia amygdalina and.
Sample collection and identification the leaves of. Nov 27, 2019 analysis of the chemical composition of vernonia and chromolaena. The objective of this study is to compare bitter leaf vernonia amygdalina and basil leaf ocimum gratissimum condiment vegetable. Chemical composition of some natural palm wine preservatives. Table 3 shows the laboratory result of the chemical composition of vernonia and chromolaena leaves. It is a vegetable, commonly used in foods and traditional medicine in tropical africa.
Phytochemical analysis and proximate composition of vernonia. Information on chemical composition of these plants can be generated for further advanced research work. Phytochemical analysis and proximate composition of vernonia amygdalina. Composition of vernoniaamygdalina and its potential health. Studies on the nutritional composition of vernonia amygdalina found its nutritional content to conform to the results obtained for green leafy vegetables. Journal of chemical engineering and industrial biotechnology v220178096. Impact of green manures of vernonia amygdalina and. The aim of this study is to isolate and elucidate the structure of some of the chemical constituents from the leaf of vernonia amygdalina and its bioactivities.
The amazing health benefits of bitter leaf vernonia. Scientists reveal that bitter leaves extract helps to reduce the blood estrogen level in the body by suppressing the activities of aromatase. Journal of chemical engineering and industrial biotechnology v220178096 83 table 2. Comparative chemical composition of leaves of some. Okpe oche 1, attah rosemary 1, ojowu john 1, edenta chidi 2, samuel m. Corrosion inhibition of stainless steel using plant. Vernonia amygdalinaare green with a char acteristic odour and bitter taste. It also went further to extract the sample using three different solvents. Azadirachta indica, vernonia amygdalina and gongronema latifolium. Bitter leaves wood ash can be used to treat and control seedborne fungi. Phytochemical and biological study on saabfat 7 with a. Chemical composition of vernonia amygdalina collected form. The amazing health benefits of bitter leaf vernonia amygdalina. The bitter and related constituents have been isolated fromvernonia amygdalina compositae, a plant ingested by wild chimpanzees possibly suffering from parasiterelated diseases in the mahale mountains national park, tanzania.
Bamigbetan department of biochemistry, college of medicine of the university of lagos,p. It is produced mainly from sorghum grain sorghum vulgare and the process of brewing involves malting, mashing, souring, fermentation and packaging locally brewed. These bioactive compounds are associated with the plants health benefits. Chemical analysis of va vernonia amygdalina organic. Leaf, medium to dark green, with or without sparse hairs above, with fine, soft, pale hairs below and. Vernonia amygdalina va is a tropical african plant of the asteraceae family and is occasionally cultivated for its medicinal uses, which include as a treatment for diarrhea, skin wounds, fever mastitis and worms infection. Several investigators have isolated and characterized a number of chemical compounds with potent biological activities from the leaves of vernonia. Phytochemical and biological study on saabfat 7 with a focus. Onugbu igbo, efo ewuro yoruba, shakwa shuwaka hausa, etidot cross river state of nigeria botanical name. Phytochemical, ethnobotany, vernonia amygdalina, therapeutic properties, ethnomedicinejournal of pharmaceutical and allied.
In my study, va chemical components were studied in order to find active chemical compositions against breast cancer. It can also act as a repellant against certain bugs, nematodes, aphids and insects. The biologicallyactive compounds of vernonia amygdalina are saponins and alkaloids, terpenes, steroids, coumarins, flavonoids, phenolic acids, lignans, xanthones and anthraquinone, edotides and sesquiterpenes. Aug 14, 2015 health benefits of bitter leaf vernonia amygdalina the leaves are widely used as a remedy for fever and are known as quinine substitute in nigeria. Extraction and characterization of bioactive compounds in vernonia. Home archives vol 8 no 18 2009 articles comparative chemical composition of leaves of some antidiabetic medicinal plants. Keywords sokoto, vernonia amygdalina, antibacterial activity, phytochemical analysis. Adsorption and thermodynamics study of the inhibition of. Comparative study of proximate, mineral and phytochemical. In vivo biochemical assessment of aqueous extracts of. Notably, medicinal plant extracts may be a potential source for treatments of breast cancer. Phytochemical and biological study on saabfat 7 with a focus on vernonia amygdalina.
Compounds isolated from vernonia amygdalina several investigators have isolated and characterized a number of chemical compounds with potent biological activities from the leaves of vernonia amygdalina. It has gained wide application in the treatment and management of various diseases. The leaves of cymbopogon citratus, pimenta racemosa, vernonia amygdalina, ocimum basilicum and the barks and the leaves of garcinia lucida and of adansonia digitata commonly used in palm wine preservation were analyzed for their chemical composition. This prompted us to isolate bioactive compounds from the flowers of this plant. Vernonia amygdalina asteraceae vernonia amygdalina, a member of the asteraceae family, is a small shrub that grows in the tropical africa with petiolate leaf of about 6 mm diameter and elliptic shape. The leaves are used either as a vegetable macerated leaves in. Vernonia amygdalina va is a woody shrub that can grow up to 5 m tall, belonging to the family of asteraceae. Chemical tests were carried out on the bitter leaf extract to identify.
Comparative chemical composition of leaves of some antidiabetic. The leaves are useful components for herbal medicine constitution. Chemical composition, phytochemical, mineral composition, energy value and functional properties of bitter leaf vernonia amygdalina and basil leaf ocimum gratissimum were determined according to aoac 2010 method. It contains many nutrients and phytochemicals such as iodine, alkaloids, anthraquinones, edotides, sesquiterpene lactones and steroid glycosides. In vivo biochemical assessment of aqueous extracts of vernonia.
Proximate analysis, mineral content, amino acid composition. Similarly, the chemical analysis revealed the presence of fat, protein, carbohydrate, fibre, ash and moisture, necessary for human growth and development vernonia amygdalina has been found useful in ethnomedicine. However, in contrast to the meters described as the height of the tree by some authors 1416, the species found around the department of wildlife and fisheries, university of ibadan. Nutritional assessment of vernonia amygdalina leaves in. Vernonia amygdalina, a member of the daisy family, is a small shrub that grows in tropical africa.
Vernonia amygdalina vernonia amygdalina are commonly called bitter leaf in english because of its bitter taste. Pdf comparative chemical analyses of vernonia amygdalina. Comparative chemical composition of leaves of some antidiabetic medicinal plants. Phytochemical composition of dry azadirachta indica and vernonia amygdalina leaves. Phytochemical analysis of vernonia amygdalina and ocimum. Analysis of the chemical composition of vernonia and chromolaena. The corrosion inhibition of stainless steel, coated with vernonia amygdalina bitter leaf and azadirachta indica dogoyaro and immersed in hydrochloric acid solution, tetraoxosulphate iv acid solution, trioxonitrate v acid solution, and exposed to the atmosphere, was investigated in. As part of an investigation into the antidiabetic mechanism of some indigenous medicinal plants, the proximate, vitamins and mineral elements and phytochemical compositions of azadirachta indica, vernonia amygdalina and gongronema latifolium were quantitatively determined using standard methods and compared. The leaves of the leaves of both plants contained varying concentrations of phytochemical components. Nutritive value and haemolytic properties in vitro of the. Jun 23, 2011 a number of chemical compounds including edotides, and sesquiterpene lactones have been isolated form the leaf of vernonia amygdalina.
Phytochemical analysis, analgesic and antipyretic properties. Vernonia amygdalina scientific classification kingdom. Diabetes control and treatment vernonia amygdalina contains biologicallyactive compounds known as coumarins, flavonoids, anthraquinone, phenolic acids, saponins, sesquiterpenes, xanthones, terpenes, steroids, lignans and edotides. Chemical composition of common leafy vegetables and. Vernonia amygdalina is among the plants used by herbalists of migori county, kenya as a dewormer. Antioxidative and chemopreventive properties of vernonia. To check the effect of bitterleaf vernonia amygdalina extract on the locally brewed sorghum beer. The cooked leaves are a staple vegetable in soup and stews of various cultures throughout equatorial africa. Vernonia amygdalina is a medicinal plant of great importance that has its fresh leaves rich in vitamins and salt hence, it is valuable in human diet. Locally brewed beer sorghum beer is an indigenous alcohol average.
Corrosion inhibition and adsorption properties of ethanol. Parameter percentage composition % of leaves ocinum gratissimum vernonia amygdalina moringa oleifera sem moisture. In general, va showed antioxidant, antimicrobial, antiparasitic, and anticancer activities. Corrosion inhibition and adsorption properties of ethanol extract of vernonia amygdalina for the corrosion of mild steel in h 2so 4 a. Figure 1 depicts the various traditional uses of vernonia amygdalina. Offor department of biochemistry, ebonyi state university, abakaliki, nigeria abstract. Leaves of vernonia amygdalina commonly known as bitter leaf is widely consumed in the subsaharan regions of africa. Vernonia amygdalina is commonly called bitter leaf because of its bitter taste. In this study, va chemical components were studied in order to find active chemical compositions against breast cancer. Pdf chemical constituents and nutrient composition of. Examples of these bioactive constituents are alkaloids, tannins, saponins.
The phytochemical screening and ethno botanical importance of the leaf of vernonia amygdalina del. Qualitative phytochemical screening of bitter leaf. Vernonia amygdalina is traditionally used in ethiopia to treat various diseases. Vernonia amygdalina has been a known food and medicinal plants used in asia and africa west africa due to its pharmacological effects antioxidant, antidiabetes, anti inflammatory, anticancer, antimalaria, and among others. Chemical constituents and nutrient composition of carica papaya and vernonia amygdalina leaf extracts.
Vernonia amygdalina is commonly called bitter leaf because of its bitter. The chemical and elemental constituents of vernonia amygdalina and azadirachta indica leaves were investigated. The mean values of the proximate composition and gross energy analysis of the leaf meal and leaf protein extracts are shown in table 1, table 2. Traditional users report that this plant possesses observable health benefits. Preliminary phytochemical screening of the nhexane. Vernonia amygdalina, a widely grown shrub plant in africa is consumed as vegetable and has high medicinal value. The chcl 3 extract after silica gel column chromatography has led to the isolation of two compounds identified as tricosane 1 and vernolide 2, while the acetone extract furnished isorhamnetin 3 and luteolin 4. Antibacterial and antioxidant compounds from the flower. Several stigmastanetype saponins such as vernoniosides a 1, a2, a 3 3, b 2, b 3, a 4. Assessment of the phytochemical constituents and invitro. Pdf comparative chemical composition of leaves of some.
Similarly, the bioflavonoid complex otherwise known as kolavion have been characterized from the seed of garcinia kola. More than 500 species of vernonia genus are distributed in africa and asia, approximately 300 in mexico, central and south america and around 16 can be found in the united states yeap et al. The use of bitterleaf vernonia amygdalina extract as a. Comparative chemical analyses of vernonia amygdalina and azadirachta indica leaves c. Comparative chemical analyses of vernonia amygdalina and azadirachta indica leaves. To compare the results from the chemical analyses of locally brewed sorghum beer with bitterleaf extract and sorghum beer brewed without bitterleaf.
The methanol extract of vernonia amygdalina, after repeated chromatography led to the isolation of a different compound, one of this compound mm4 is partially characterized based on the spectral data ir, 1h nmr, c nmr, and dept and extracts from vernonia amygdalina has been shown to have antimicrobial activity. The anticancer activities of vernonia amygdalina extract in. Nutritive value and haemolytic properties in vitro of. The secondary metabolites in the leaf were identified to establish a relationship between them and their therapeutic properties. Vernonia amygdalina is a shrub that grows predominantly in. The antioxidant, antiinflammatory and analgesic activities of its acetone leaf extract were evaluated in this study to validate its folkloric use.
1423 61 596 224 916 232 960 1059 1512 1267 786 1034 493 911 477 462 404 261 1292 48 16 996 483 1351 1041 816 1508 600 1014 887 981 1385 1431 489 1164 1466 1205 1063 985 308 1146 511